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CHROMATIN-MEDIATED TRANSCRIPTIONAL REPRESSION IN YEAST

被引：89
作者：
ROTH, SY
机构：
[1] Department of Biochemistry and Molecular Biology, University of Texas MD Anderson Cancer Center, Houston
来源：
CURRENT OPINION IN GENETICS & DEVELOPMENT | 1995年 / 5卷 / 02期
基金：
美国国家卫生研究院;
关键词：
D O I：
10.1016/0959-437X(95)80004-2
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Chromatin is linked to two modes of transcriptional repression in yeast: silencing at the HM loci and telomeres, and repression by the global regulator complex Ssn6/Tup1. In both cases, unique chromatin configurations appear to be orchestrated by multiprotein complexes targeted to particular regions through interactions with specific DNA-binding proteins, such as RAP1, the origin-recognition complex, and alpha 2.
引用
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页码：168 / 173
页数：6
相关论文
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