INVOLVEMENT OF SWIMMING-INDUCED ACUTE STRESS IN THE SENSITIVITY OF RAT VAS-DEFERENS TO NOREPINEPHRINE

被引：7

作者：

BISPO, DLN

PEREIRA, OCM

机构：

[1] Department of Pharmacology, Institute of Bioscience-São Paulo State University (UNESP), Botucatu

来源：

GENERAL PHARMACOLOGY-THE VASCULAR SYSTEM | 1992年 / 23卷 / 06期

关键词：

D O I：

10.1016/0306-3623(92)90298-X

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

1. The effects of swimming-induced stress on rat sensitivity to norepinephrine 2. Through microscopic analysis of the stomach from swimming stressed rats significant ulceration was observed, confirming that the stress situation was really present. 3. Sensitivity to norepinephrine either in the presence or in the absence of cocaine and propranolol in acutely swimming stressed rats was not altered significantly. 4. Bilateral adrenalectomy was performed in rats 2 days before swimming and acute stress resulted in a supersensitivity to norepinephrine, indicating that adrenal glands may, at least, partially mediate the sensitivity to this drug in vasa deferentia isolated from these animals.

引用

页码：1125 / 1128

页数：4

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