14-3-3-PROTEINS - STRUCTURE RESOLVED, FUNCTIONS LESS CLEAR

被引:15
作者
MARAIS, R
MARSHALL, C
机构
[1] Richard Marais and Chris Marshall, CRC Centre for Cell and Molecular Biology, The Institute of Cancer Research, London, SW3 6JB
关键词
D O I
10.1016/S0969-2126(01)00209-X
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The crystal structures of 14-3-3 proteins reveal that they form dimers with a deep groove running along the length of the dimer. The location of conserved residues in this groove suggests that it plays an essential role in the adaptor functions of these proteins.
引用
收藏
页码:751 / 753
页数:3
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