NUCLEAR-DNA POLYMORPHISM IN A MANDENKA POPULATION FROM SENEGAL - COMPARISON WITH 8 OTHER HUMAN-POPULATIONS

被引:35
作者
POLONI, ES
EXCOFFIER, L
MOUNTAIN, JL
LANGANEY, A
CAVALLISFORZA, LL
机构
[1] MUSEE HOMME PARIS, CNRS, URA 49, F-75116 PARIS, FRANCE
[2] STANFORD UNIV, SCH MED, DEPT GENET, STANFORD, CA 94305 USA
关键词
D O I
10.1111/j.1469-1809.1995.tb01605.x
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
A large and ethnically well defined Mandenka sample from Senegal is analysed for 80 nuclear DNA RPLPs, and compared with eight previously studied human populations. A high level of genetic diversity is found in this sample, comparable to that observed in two African Pygmy samples, but lower than that of a European sample. High population variation is observed for most markers. A neutrality test reveals that the markers used in this study can be considered as neutral. A high correlation is found between genetic and geographic distances (r = 0.62), suggesting that geography does also affect long range population genetic relationships and is an important factor behind differentiation among human populations.
引用
收藏
页码:43 / 61
页数:19
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共 65 条
  • [21] Ehret C., 1984, HUNTERS FARMERS, P26
  • [22] EWENS WJ, 1972, THEOR POPUL BIOL, V3, P87, DOI 10.1016/0040-5809(72)90035-4
  • [23] EXCOFFIER L, 1991, HUM BIOL, V63, P273
  • [24] EXCOFFIER L, 1989, AM J HUM GENET, V44, P73
  • [25] EXCOFFIER L, 1987, YEARB PHYS ANTHROPOL, V30, P151
  • [26] EXCOFFIER L, 1992, GENETICS, V131, P479
  • [27] A TECHNIQUE FOR RADIOLABELING DNA RESTRICTION ENDONUCLEASE FRAGMENTS TO HIGH SPECIFIC ACTIVITY
    FEINBERG, AP
    VOGELSTEIN, B
    [J]. ANALYTICAL BIOCHEMISTRY, 1983, 132 (01) : 6 - 13
  • [28] POPULATION BOTTLENECKS IN POLYNESIA REVEALED BY MINISATELLITES
    FLINT, J
    BOYCE, AJ
    MARTINSON, JJ
    CLEGG, JB
    [J]. HUMAN GENETICS, 1989, 83 (03) : 257 - 263
  • [29] Greenberg J., 1963, LANGUAGES AFRICA
  • [30] HORAI S, 1993, MOL BIOL EVOL, V10, P23