SYNTHESIS OF CYCLOPROPANE-FUSED DIDEOXYCARBOCYCLIC NUCLEOSIDES STRUCTURALLY RELATED TO NEPLANOCIN-C

被引：81

作者：

RODRIGUEZ, JB ^{[1
]}

MARQUEZ, VE ^{[1
]}

NICKLAUS, MC ^{[1
]}

BARCHI, JJ ^{[1
]}

机构：

[1] NCI, DIV CANC TREATMENT, DEV THERAPEUT PROGRAM, MED CHEM LAB, BETHESDA, MD 20892 USA

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 39期

关键词：

D O I：

10.1016/S0040-4039(00)73718-X

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The syntheses of five novel carbocyclic dideoxynucleosides with a bicyclo[3.1.0]hexane skeleton was accomplished via a Mitsunobu-type coupling reaction with various heterocyclic bases. These compounds appear to prefer a typical nucleoside northern conformation.

引用

页码：6233 / 6236

页数：4