GENETIC DRIFT OF EQUINE-2 INFLUENZA-A VIRUS (H3N8), 1963-1988 - ANALYSIS BY OLIGONUCLEOTIDE MAPPING

被引:13
作者
BERG, M
DESSELBERGER, U
ABUSUGRA, IA
KLINGEBORN, B
LINNE, T
机构
[1] SWEDISH UNIV AGR SCI,DEPT VET MICROBIOL,VIROL SECT,BOX 585,S-75123 UPPSALA,SWEDEN
[2] NATL VET INST,CTR BIOMED,DEPT VIROL,S-75123 UPPSALA,SWEDEN
[3] UNIV GLASGOW,DEPT VIROL,GLASGOW G11 5JR,SCOTLAND
关键词
D O I
10.1016/0378-1135(90)90109-9
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Comparative analysis by RNA oligonucleotide fingerprints of total genomic RNA as well as the individual RNA segments of equine 2 influenza A virus strains from 1963, 1968, 1979, 1984, 1987 and 1988 revealed genetic diversity. Strains from the epizootic outbreak during 1978-1979 showed minor differences among their genomes. The Swedish isolates from 1979 up to 1988 showed increasing genomic heterogeneity indicating genetic drift. © 1990.
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页码:225 / 236
页数:12
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