THERAPEUTIC APPLICATIONS OF OLIGONUCLEOTIDES

被引:48
作者
CROOKE, ST
机构
[1] ISIS Pharmaceuticals, Carlsbad, CA, 92008
来源
BIO-TECHNOLOGY | 1992年 / 10卷 / 08期
关键词
D O I
10.1038/nbt0892-882
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
This review focuses strictly on the pharmacodynamic considerations of the use of oligonucleotides designed to interact with nucleic acids as therapeutics. The objectives are to place oligonucleotide therapeutics in the context of modern drug discovery and development and to summarize recent progress.
引用
收藏
页码:882 / 886
页数:5
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