CONTINUOUS ENZYMATIC-SYNTHESIS OF 2'-DEOXYTHYMIDINE-5'(ALPHA-D-GLUCOPYRANOSYL)DIPHOSPHATE

被引：21

作者：

ZERVOSEN, A ^{[1
]}

ELLING, L ^{[1
]}

KULA, MR ^{[1
]}

机构：

[1] FORSCHUNGSZENTRUM JULICH, UNIV DUSSELDORF, INST ENZYMTECHNOL, D-52404 JULICH, GERMANY

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 1994年 / 33卷 / 05期

关键词：

D O I：

10.1002/anie.199405711

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The preparation of primary nucleotide sugars like 1 with sucrose synthase, a glycosyl transferase in plants, provides an alternative in enzymatic synthesis to the use of highly specific pyrophosphorylases. In an enzyme membrane reactor a continuous synthesis can be performed on preparative scale. (Figure Presented.) Copyright © 1994 by VCH Verlagsgesellschaft mbH, Germany

引用

页码：571 / 572

页数：2

共 14 条

[1] URIDINE DIPHOSPHATE GLUCOSE - THE COENZYME OF THE GALACTOSE GLUCOSE PHOSPHATE ISOMERIZATION [J].

CARDINI, CE ;

PALADINI, AC ;

CAPUTTO, R ;

LELOIR, LF .

NATURE, 1950, 165 (4188) :192-192

[2] INVESTIGATION OF SUCROSE SYNTHASE FROM RICE FOR THE SYNTHESIS OF VARIOUS NUCLEOTIDE SUGARS AND SACCHARIDES [J].

ELLING, L ;

GROTHUS, M ;

KULA, MR .

GLYCOBIOLOGY, 1993, 3 (04) :349-355

[3] PURIFICATION OF SUCROSE SYNTHASE FROM RICE AND ITS PROTEIN-CHEMICAL CHARACTERIZATION [J].

ELLING, L ;

KULA, MR .

JOURNAL OF BIOTECHNOLOGY, 1993, 29 (03) :277-286

[4]

ELLING L, 1993, IN PRESS ENZYME MICR

[5]

GRISEBACH H, 1978, ADV CARBOHYD CHEM BI, V35, P81

[6] NUCLEOSIDE PHOSPHATE SUGARS - SYNTHESES ON PRACTICAL SCALES FOR USE AS REAGENTS IN THE ENZYMATIC PREPARATION OF OLIGOSACCHARIDES AND GLYCOCONJUGATES [J].

HEIDLAS, JE ;

WILLIAMS, KW ;

WHITESIDES, GM .

ACCOUNTS OF CHEMICAL RESEARCH, 1992, 25 (07) :307-314

[7] ENZYME-CATALYZED OLIGOSACCHARIDE SYNTHESIS [J].

ICHIKAWA, Y ;

LOOK, GC ;

WONG, CH .

ANALYTICAL BIOCHEMISTRY, 1992, 202 (02) :215-238

[8]

KLAFFKE W, COMMUNICATION

[9]

KORNFELD S, 1961, J BIOL CHEM, V236, P1791

[10] ENZYMATIC-SYNTHESIS AND ISOLATION OF THYMIDINE DIPHOSPHATE-6-DEOXY-D-XYLO-4-HEXULOSE AND THYMIDINE DIPHOSPHATE-L-RHAMNOSE - PRODUCTION USING CLONED GENE-PRODUCTS AND SEPARATION BY HPLC [J].

MARUMO, K ;

LINDQVIST, L ;

VERMA, N ;

WEINTRAUB, A ;

REEVES, PR ;

LINDBERG, AA .

EUROPEAN JOURNAL OF BIOCHEMISTRY, 1992, 204 (02) :539-545

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