BCL-2 - A REPRESSOR OF LYMPHOCYTE DEATH

被引:222
作者
KORSMEYER, SJ
机构
[1] Stanley J. Korsmeyer is at the Howard Hughes Medical Institute, Washington University School of Medicine, St Louis, MO 63110
来源
IMMUNOLOGY TODAY | 1992年 / 13卷 / 08期
关键词
D O I
10.1016/0167-5699(92)90037-8
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
The genes and mechanisms that control programmed cell death are currently the subject of intense study. The bcl-2 gene, a repressor of lymphocyte death, is perhaps the best understood of the programmed cell death associated genes. Here, Stanley Korsmeyer provides a brief overview of bcl-2, concentrating on its roles in B- and T-cell development and in oncogenesis.
引用
收藏
页码:285 / 288
页数:4
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