STABILITY-INDICATING ASSAY FOR PIVMECILLINAM HYDROCHLORIDE AND PIVMECILLINAM HYDROCHLORIDE CAPSULES

被引：7

作者：

HAGEL, RB

WAYSEK, EH

机构：

[1] Quality Control Department, Hoffmann-La Roche Inc., Nutley, NJ 07110

来源：

JOURNAL OF CHROMATOGRAPHY | 1979年 / 178卷 / 01期

关键词：

D O I：

10.1016/S0021-9673(00)89700-9

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A high-pressure liquid chromatographic assay was developed for pivmecillinam hydrochloride and pivmecillinam hydrochloride capsules. The method separates 5 reported degradation products and a number of esterified, related compounds. The accuracy of this method is comparable to the published UV assay, and the relative SD of a series of 6 replicate assays was better than .+-. 0.7%.

引用

页码：97 / 104

页数：8

共 8 条

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HAGEL, RB ;

WAYSEK, EH ;

HUMPHREY, D .

JOURNAL OF CHROMATOGRAPHY, 1979, 170 (02) :391-398

[2]

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[3]

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[7]

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[8]

WILLIAMS JD, 1977, J ANTIMICROB CHEM SB, V3, P1

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