SOLUTION STRUCTURE OF THE ANTITUMOR ANTIBIOTIC NEOCARZINOSTATIN, A CHROMOPHORE PROTEIN COMPLEX

被引：40

作者：

TANAKA, T

HIRAMA, M

FUJITA, K

IMAJO, S

ISHIGURO, M

机构：

[1] TOHOKU UNIV,FAC SCI,DEPT CHEM,SENDAI,MIYAGI 980,JAPAN

[2] SUNTORY INST BIOMED RES,SHIMAMOTO,OSAKA 618,JAPAN

[3] JEOL LTD,DIV ANALYT INSTRUMENTS,TOKYO 196,JAPAN

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1993年 / 15期

关键词：

D O I：

10.1039/c39930001205

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The chromophore-binding structure of the neocarzinostatin complex is determined for the first time by two-dimensional H-1 NMR spectroscopy, and reveals the elements of the specific binding and the stabilization interactions of the unstable dienediyne chromophore by the apoprotein.

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收藏

页码：1205 / 1207

页数：3

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