ENANTIOSELECTIVE ONE-POT SYNTHESIS OF BETA-LACTAMS FROM ACHIRAL 2-PYRIDYLTHIOESTERS AND AROMATIC IMINES

被引：20

作者：

ANNUNZIATA, R

BENAGLIA, M

CINQUINI, M

COZZI, F

机构：

[1] UNIV MILAN,CTR CNR,I-20133 MILAN,ITALY

[2] UNIV MILAN,DIPARTIMENTO CHIM ORGAN & IND,I-20133 MILAN,ITALY

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 04期

关键词：

D O I：

10.1016/0040-4039(94)02316-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The enolates derived from 2-pyridylthioesters by reaction with BCl3.SMe(2) and enantiomerically pure aminoalcohols react with aromatic imines in an enantioselective fashion (ee up to 78%) to afford beta-lactams in a convenient one-pot procedure.

引用

页码：613 / 616

页数：4

共 11 条

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