PREVIOUS PET OWNERSHIP AND PAGETS-DISEASE

被引：17

作者：

HOLDAWAY, IM

IBBERTSON, HK

WATTIE, D

SCRAGG, R

GRAHAM, P

机构：

[1] SCH MED AUCKLAND,DEPT MED,ENDOCRINOL SECT,AUCKLAND,NEW ZEALAND

[2] SCH MED AUCKLAND,DEPT COMMUNITY HLTH,AUCKLAND,NEW ZEALAND

来源：

BONE AND MINERAL | 1990年 / 8卷 / 01期

基金：

英国医学研究理事会;

关键词：

Paget's disease; Paramyxovirus; Pets; Slow virus;

D O I：

10.1016/0169-6009(91)90140-U

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The relationship between pet ownership and Paget's disease (PD) of bone was investigated in 112 patients with PD who were matched with a similar number of community-based controls. There was a significantly increased frequency of dog ownership by patients with PD aged <60 years. Multivariate logistic regression analysis revealed that there was a significant age-related increase in risk of PD associated with past or present ownership of either dogs or cats, with younger patients having the greatest risk. These results suggest that slow virus infection of osteoclasts by paramyxoviruses acquired from pets may contribute to the development of Paget's disease in the younger patient. © 1990.

引用

页码：53 / 58

页数：6