EXPRESSION OF THE YEAST DNA PRIMASE GENE, PRI1, IS REGULATED WITHIN THE MITOTIC CELL-CYCLE AND IN MEIOSIS

被引:27
作者
JOHNSTON, LH [1 ]
WHITE, JHM [1 ]
JOHNSON, AL [1 ]
LUCCHINI, G [1 ]
PLEVANI, P [1 ]
机构
[1] UNIV MILANO,DIPARTIMENTO GENET & BIOL MICRORGANISMI,I-20133 MILAN,ITALY
来源
MOLECULAR & GENERAL GENETICS | 1990年 / 221卷 / 01期
关键词
Cell cycle; DNA primase; Meiosis; Yeast;
D O I
10.1007/BF00280366
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Mitotic cultures synchronised either by a feed-starve protocol or by elutriation have been used to show that the Saccharomyces cerevisiae DNA primase I gene is periodically expressed in the cell cycle. The transcript increases many-fold in late G1 and reaches a peak at the same time as four other genes essential for DNA synthesis, CDC8, CDC9, CDC21 and POL1. The primase I transcript is also regulated in meiosis, reaching maximal levels during premeiotic DNA synthesis. © 1990 Springer-Verlag.
引用
收藏
页码:44 / 48
页数:5
相关论文
共 17 条