4-AMINOBUTYRATE-2-OXOGLUTARATE AMINOTRANSFERASE IN BLOOD-PLATELETS

被引：62

作者：

WHITE, HL

机构：

[1] Pharmacology Department, Wellcome Research Laboratories, Research Triangle Park

来源：

SCIENCE | 1979年 / 205卷 / 4407期

关键词：

D O I：

10.1126/science.462176

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Platelet lysates obtained from blood of humans, dogs, and rats catalyzed the transamination of 4-aminobutyrate with 2-oxoglutarate as cosubstrate. Human platelet 4-aminobutyrate:2-oxoglutarate aminotransferase (36.5 ± 3.2 picomoles per minute per milligram of platelet protein) resembled the brain enzyme in kinetic properties and in response to cofactors and inhibitors.

引用

页码：696 / 698

页数：3

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