KINETIC AND ULTRAVIOLET SPECTROSCOPIC STUDIES OF ACTIVE-SITE MUTANTS OF DELTA-5-3-KETOSTEROID ISOMERASE

[1] Ackers G K, 1970, Adv Protein Chem, V24, P343, DOI 10.1016/S0065-3233(08)60245-4

[2] Alder R. W., 1971, MECHANISMS ORGANIC C, P248

[3] Batzold F H, 1976, Adv Enzyme Regul, V14, P243, DOI 10.1016/0065-2571(76)90016-9

[4] PROTON NUCLEAR MAGNETIC-RESONANCE STUDIES OF PSEUDOMONAS-TESTOSTERONI 3-OXO-DELTA-5-STEROID ISOMERASE AND ITS INTERACTION WITH 17-BETA-ESTRADIOL [J]. BIOCHEMISTRY, 1982, 21 (23) : 5816 - 5825

[5] BENSON AM, 1975, J BIOL CHEM, V250, P276

[6] IRREVERSIBLE ACTIVE-SITE-DIRECTED INHIBITION OF DELTA-5-3-KETOSTEROID ISOMERASE BY STEROIDAL 17-BETA-OXIRANES - EVIDENCE FOR 2 MODES OF BINDING IN STEROID-ENZYME COMPLEXES [J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1980, 95 (03) : 1131 - 1137

[7] MODIFICATION OF AN ENZYME CARBOXYLATE RESIDUE IN THE INHIBITION OF 3-OXO-DELTA-5-STEROID ISOMERASE BY (3S)-SPIRO[5-ALPHA-ANDROSTANE-3,2'-OXIRANE]-17-BETA-OL - IMPLICATIONS FOR THE MECHANISM OF ACTION [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1984, 106 (17) : 4957 - 4962

[8] DETECTION OF A TRANSIENT ENZYME STEROID COMPLEX DURING ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITION OF 3-OXO-DELTA-5-STEROID ISOMERASE [J]. BIOCHEMISTRY, 1986, 25 (18) : 5159 - 5164

[9] USE OF ISOTOPE EFFECTS TO DEDUCE THE CHEMICAL MECHANISM OF FUMARASE [J]. BIOCHEMISTRY, 1980, 19 (19) : 4506 - 4513

[10] AFFINITY ALKYLATION OF 3-OXO- DELTA-5-STEROID ISOMERASE BY STEROIDAL 3-BETA-OXIRANES - IDENTIFICATION OF THE MODIFIED AMINO-ACID BY REDUCTION WITH HYDROXYBOROHYDRIDE [J]. BIOCHEMISTRY, 1987, 26 (08) : 2263 - 2269

[1] Ackers G K, 1970, Adv Protein Chem, V24, P343, DOI 10.1016/S0065-3233(08)60245-4

[2] Alder R. W., 1971, MECHANISMS ORGANIC C, P248

[3] Batzold F H, 1976, Adv Enzyme Regul, V14, P243, DOI 10.1016/0065-2571(76)90016-9

[4] PROTON NUCLEAR MAGNETIC-RESONANCE STUDIES OF PSEUDOMONAS-TESTOSTERONI 3-OXO-DELTA-5-STEROID ISOMERASE AND ITS INTERACTION WITH 17-BETA-ESTRADIOL [J]. BIOCHEMISTRY, 1982, 21 (23) : 5816 - 5825

[5] BENSON AM, 1975, J BIOL CHEM, V250, P276

[6] IRREVERSIBLE ACTIVE-SITE-DIRECTED INHIBITION OF DELTA-5-3-KETOSTEROID ISOMERASE BY STEROIDAL 17-BETA-OXIRANES - EVIDENCE FOR 2 MODES OF BINDING IN STEROID-ENZYME COMPLEXES [J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1980, 95 (03) : 1131 - 1137

[7] MODIFICATION OF AN ENZYME CARBOXYLATE RESIDUE IN THE INHIBITION OF 3-OXO-DELTA-5-STEROID ISOMERASE BY (3S)-SPIRO[5-ALPHA-ANDROSTANE-3,2'-OXIRANE]-17-BETA-OL - IMPLICATIONS FOR THE MECHANISM OF ACTION [J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1984, 106 (17) : 4957 - 4962

[8] DETECTION OF A TRANSIENT ENZYME STEROID COMPLEX DURING ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITION OF 3-OXO-DELTA-5-STEROID ISOMERASE [J]. BIOCHEMISTRY, 1986, 25 (18) : 5159 - 5164

[9] USE OF ISOTOPE EFFECTS TO DEDUCE THE CHEMICAL MECHANISM OF FUMARASE [J]. BIOCHEMISTRY, 1980, 19 (19) : 4506 - 4513

[10] AFFINITY ALKYLATION OF 3-OXO- DELTA-5-STEROID ISOMERASE BY STEROIDAL 3-BETA-OXIRANES - IDENTIFICATION OF THE MODIFIED AMINO-ACID BY REDUCTION WITH HYDROXYBOROHYDRIDE [J]. BIOCHEMISTRY, 1987, 26 (08) : 2263 - 2269