共 21 条
- [21] Viola Magni M.P., 1986, CELL BIOCHEM FUNCT, V4, P283
CHROMATIN PHOSPHOLIPID CHANGES DURING RAT-LIVER DEVELOPMENT
被引：23
作者：
ALBI, E
MAGNI, MV
LAZZARINI, R
GAHAN, PB
机构：
[1] KINGS COLL LONDON, DIV BIOSPHERE SCI, CAMPDEN HILL RD, LONDON W8 7AH, ENGLAND
[2] UNIV PERUGIA, IST PATOL GEN, I-06100 PERUGIA, ITALY
关键词：
CHROMATIN;
PHOSPHOLIPIDS;
HEPATOCYTES;
DEVELOPMENT;
D O I：
10.1002/cbf.290090209
中图分类号：
Q5 [生物化学];
Q7 [分子生物学];
学科分类号：
071010 ;
081704 ;
摘要：
The chromatin extracted from rat hepatocytes of different ages has been shown to contain a phospholipid fraction representing 0.47-0.59 per cent of total chromatin in newborn animals and 0.22 per cent in 45-day-old animals. No such age-related differences are observed in the nuclei. The phospholipid composition of the nuclei at different ages shows a higher level of sphingomyelin and a lower level of phosphatidylserine in newborn than in adult animals. Chromatin phospholipids have a completely different composition from that of nuclei with respect to age, particularly in newborn rats, where there is a decrease in phosphatidylcholine and an increase in phosphatidylserine.
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页码：119 / 123
页数：5
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