2-CHLOROMETHYL-4-NITROPHENYL ALPHA-D-GLUCOPYRANOSIDE - AN ENZYME-ACTIVATED IRREVERSIBLE INHIBITOR OF YEAST ALPHA-GLUCOSIDASE

被引:11
作者
BRIGGS, JC [1 ]
HAINES, AH [1 ]
TAYLOR, RJK [1 ]
机构
[1] UNIV E ANGLIA,SCH CHEM SCI,NORWICH NR4 7TJ,NORFOLK,ENGLAND
关键词
D O I
10.1039/c39920001039
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
2-Chloromethyl-4-nitrophenyl alpha-D-glucopyranoside, prepared by a novel, four-step route from 2-methylphenyl alpha-D-glucopyranoside tetraacetate, is highly effective as an enzyme-activated irreversible inhibitor of yeast alpha-glucosidase and is much superior in this respect to 2-chloromethylphenyl alpha-D-glucopyranoside.
引用
收藏
页码:1039 / 1041
页数:3
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