2-CHLOROMETHYL-4-NITROPHENYL ALPHA-D-GLUCOPYRANOSIDE - AN ENZYME-ACTIVATED IRREVERSIBLE INHIBITOR OF YEAST ALPHA-GLUCOSIDASE

被引：11

作者：

BRIGGS, JC ^{[1
]}

HAINES, AH ^{[1
]}

TAYLOR, RJK ^{[1
]}

机构：

[1] UNIV E ANGLIA,SCH CHEM SCI,NORWICH NR4 7TJ,NORFOLK,ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1992年 / 15期

关键词：

D O I：

10.1039/c39920001039

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

2-Chloromethyl-4-nitrophenyl alpha-D-glucopyranoside, prepared by a novel, four-step route from 2-methylphenyl alpha-D-glucopyranoside tetraacetate, is highly effective as an enzyme-activated irreversible inhibitor of yeast alpha-glucosidase and is much superior in this respect to 2-chloromethylphenyl alpha-D-glucopyranoside.

引用

页码：1039 / 1041

页数：3

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