MORTALITY OF FILLING STATION ATTENDANTS

被引:35
作者
LAGORIO, S
FORASTIERE, F
IAVARONE, I
RAPITI, E
VANACORE, N
PERUCCI, CA
CARERE, A
机构
[1] LATIUM REG HLTH AUTH,EPIDEMIOL UNIT,ROME,ITALY
[2] UNIV ROMA LA SAPIENZA,DEPT NEUROL,ROME,ITALY
关键词
BENZENE; COHORT; GASOLINE EXHAUSTS; GASOLINE VAPORS; OCCUPATIONAL CANCER;
D O I
10.5271/sjweh.1389
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
OBJECTIVES - Gasoline contains established human carcinogens, such as benzene. The health impact of exposure to this fuel, however, has not been fully elucidated. We report on the mortality of a cohort of 2665 filling station managers from the Latium region (Italy). METHODS - This is the first workplace-based cohort of gas station attendants. However, only self-employed individuals were available for study (about 50% of the whole work force). The follow-up period extended from 1981 through 1992. The mortality experience of the cohort was compared with that of the regional population. RESULTS - The overall analysis for standardized mortality ratios (SMR) showed a significantly decreased mortality from all causes, mainly due to a deficit of cardiovascular diseases and malignant neoplasms. Nonsignificantly increased risks for esophageal cancer [SMR 241, 90% confidence interval (90% CI) 82-551], brain cancer (SMR 195, 90% CI 77-401) and non-Hodgkin's lymphoma (SMR 173, 90% CI 47-448) were found for the men; mortality due to lung cancer and leukemia was lower than expected, and no kidney cancer death was recorded. Among the attendants of small stations (characterized by a small number of employees and high sales of gasoline per full-time employee), the SMR values for esophageal cancer (for men SMR 351, 90% CI 120-803) and brain cancer (for men and women SMR 266, 90% CI 105-559) showed increased values. CONCLUSIONS - Filling station attendants are exposed to gasoline vapors and seem at risk of cancer of various sites. Due to the power limitations of this study, however, a precise estimate of the risk for many causes of death was not achievable. Further cohort studies of greater size are warranted.
引用
收藏
页码:331 / 338
页数:8
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