OPPORTUNISTIC NOSOCOMIAL MULTIPLY RESISTANT BACTERIAL-INFECTIONS - THEIR TREATMENT AND PREVENTION

One of the most difficult problems confronting the clinician who deals with nosocomial infections is that of micobial resistance. The predominant nosocomial infections (urinary tract infections, pneumonia, septicaemia, surgical wound infections) involve increasing numbers of Gram-positive bacteria, Staphylococcus epidermidis, Corynebacterium jeikeiumor resistant enterococci as well as new multiresistant Gram-negative bacilli such as Xanthomonas maltophilia. Acinetobacter baumannii and Alcaligenes xylosoxydans. The emergence and spread of Klebsiella pneumoniae and other Enterobacteriaceae producing novel plasmid-mediated β-lactamases active against third-generation cephalosporins contribute to the difficulty in treating nosocomial infections. © 1993 The British Society for Antimicrobial Chemotheraphy.