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PRENATAL ALCOHOL EXPOSURE ATTENUATES PENTYLENETETRAZOL-INDUCED CONVULSIONS IN RATS

被引：9
作者：
ABEL, EL
BERMAN, RF
CHURCH, MW
机构：
[1] WAYNE STATE UNIV,FETAL ALCOHOL RES CTR,DEPT PSYCHOL,DETROIT,MI 48201
[2] WAYNE STATE UNIV,FETAL ALCOHOL RES CTR,DEPT OBSTET GYNECOL,DETROIT,MI 48201
来源：
ALCOHOL | 1993年 / 10卷 / 02期
关键词：
PRENATAL ALCOHOL; PENTYLENETETRAZOL; CONVULSIONS; RATS;
D O I：
10.1016/0741-8329(93)90096-7
中图分类号：
R194 [卫生标准、卫生检查、医药管理];
学科分类号：
摘要：
Female rats prenatally exposed to alcohol were tested at 35 days of age for susceptibility to pentylenetetrazol (PTZ)-induced convulsions. There was a significant dose-response effect of PTZ. Contrary to expectations, alcohol-exposed females were slightly but still significantly less convulsion-prone than pair-fed controls. These results suggest prenatal alcohol exposure reduces the susceptibility to convulsions in rats.
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页码：155 / 157
页数：3
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