PRENATAL ALCOHOL EXPOSURE ATTENUATES PENTYLENETETRAZOL-INDUCED CONVULSIONS IN RATS

被引：9

作者：

ABEL, EL

BERMAN, RF

CHURCH, MW

机构：

[1] WAYNE STATE UNIV,FETAL ALCOHOL RES CTR,DEPT PSYCHOL,DETROIT,MI 48201

[2] WAYNE STATE UNIV,FETAL ALCOHOL RES CTR,DEPT OBSTET GYNECOL,DETROIT,MI 48201

来源：

ALCOHOL | 1993年 / 10卷 / 02期

关键词：

PRENATAL ALCOHOL; PENTYLENETETRAZOL; CONVULSIONS; RATS;

D O I：

10.1016/0741-8329(93)90096-7

中图分类号：

R194 [卫生标准、卫生检查、医药管理];

学科分类号：

摘要：

Female rats prenatally exposed to alcohol were tested at 35 days of age for susceptibility to pentylenetetrazol (PTZ)-induced convulsions. There was a significant dose-response effect of PTZ. Contrary to expectations, alcohol-exposed females were slightly but still significantly less convulsion-prone than pair-fed controls. These results suggest prenatal alcohol exposure reduces the susceptibility to convulsions in rats.

引用

页码：155 / 157

页数：3

共 22 条

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