ETHNIC DIFFERENCE IN DRUG-METABOLISM - DEBRISOQUINE 4-HYDROXYLATION IN CAUCASIANS AND ORIENTALS

被引：50

作者：

KALOW, W ^{[1
]}

OTTON, SV ^{[1
]}

KADAR, D ^{[1
]}

ENDRENYI, L ^{[1
]}

INABA, T ^{[1
]}

机构：

[1] UNIV TORONTO,FAC MED,DEPT PHARMACOL,TORONTO M5S 1A8,ONTARIO,CANADA

来源：

CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY | 1980年 / 58卷 / 09期

关键词：

D O I：

10.1139/y80-173

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

收藏

页码：1142 / 1144

页数：3

相关论文

共 12 条

[1] CONTRIBUTION OF ENVIRONMENTAL-FACTORS TO VARIABILITY IN HUMAN DRUG-METABOLISM
DOLLERY, CT
FRASER, HS
MUCKLOW, JC
BULPITT, CJ
[J]. DRUG METABOLISM REVIEWS, 1979, 9 (02) : 207 - 220
[2] EICHELBAUM M, 1978, BIOL OXIDATION NITRO, P113
[3] GAS-LIQUID-CHROMATOGRAPHIC ELECTRON-CAPTURE DETERMINATION OF SOME MONOSUBSTITUTED GUANIDO-CONTAINING DRUGS
ERDTMANSKY, P
GOEHL, TJ
[J]. ANALYTICAL CHEMISTRY, 1975, 47 (04) : 750 - 752
[4] POLYMORPHISMS OF OXIDATION AT CARBON CENTERS OF DRUGS AND THEIR CLINICAL SIGNIFICANCE
IDLE, JR
SMITH, RL
[J]. DRUG METABOLISM REVIEWS, 1979, 9 (02) : 301 - 317
[5] DEFICIENT METABOLISM OF DEBRISOQUINE AND SPARTEINE
INABA, T
OTTON, SV
KALOW, W
[J]. CLINICAL PHARMACOLOGY & THERAPEUTICS, 1980, 27 (04) : 547 - 549
[6] KALOW W, 1979, CLIN PHARMACOL THER, V26, P766
[7] KALOW W, 1978, CLIN PHARMACOL THER, V24, P576
[8] POLYMORPHIC HYDROXYLATION OF DEBRISOQUINE IN MAN
MAHGOUB, A
IDLE, JR
DRING, LG
LANCASTER, R
SMITH, RL
[J]. LANCET, 1977, 2 (8038) : 584 - 586
[9] POPULATION AND FAMILIAL STUDY OF THE DEFECTIVE ALICYCLIC HYDROXYLATION OF DEBRISOQUINE AMONG EGYPTIANS
MAHGOUB, A
IDLE, JR
SMITH, RL
[J]. XENOBIOTICA, 1979, 9 (01) : 51 - 56
[10] DETERMINATION OF DEBRISOQUIN AND ITS 4-HYDROXY METABOLITE IN PLASMA BY GAS CHROMATOGRAPHY MASS SPECTROMETRY
MALCOLM, SL
MARTEN, TR
[J]. ANALYTICAL CHEMISTRY, 1976, 48 (06) : 807 - 809