TRADITIONAL MEDICINAL-PLANTS OF THAILAND .22. CYTOTOXIC AND ANTIMALARIAL ALKALOIDS FROM THE BULBS OF CRINUM-AMABILE

被引：171

作者：

LIKHITWITAYAWUID, K

ANGERHOFER, CK

CHAI, HB

PEZZUTO, JM

CORDELL, GA

机构：

[1] UNIV ILLINOIS, COLL PHARM, DEPT MED CHEM & PHARMACOGNOSY, PROGRAM COLLABORAT RES PHARMACEUT SCI, CHICAGO, IL 60612 USA

[2] CHULALONGKORN UNIV, FAC PHARMACEUT SCI, DEPT PHARMACOGNOSY, BANGKOK 5, THAILAND

来源：

JOURNAL OF NATURAL PRODUCTS | 1993年 / 56卷 / 08期

关键词：

D O I：

10.1021/np50098a017

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

From the bulbs of Crinum amabile (Amaryllidaceae), a new alkaloid (-)-amabiline [1], together with the known alkaloids (-)-lycorine [2], (-)-buphanisine [3], (-)-augustine [4], and (+)-crinamine [5], were isolated. The structural characterization of 1 and the revised H-1- and C-13-nmr assignments of 2 are discussed. Alkaloids 2, 4, and 5 were found to be the principal cytotoxic and antimalarial constituents.

引用

页码：1331 / 1338

页数：8

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