HERPES-SIMPLEX VIRUS IN IMMUNOCOMPROMISED PATIENTS - GROWING EVIDENCE OF DRUG-RESISTANCE

被引：33

作者：

EPSTEIN, JB ^{[1
]}

SCULLY, C ^{[1
]}

机构：

[1] UNIV BRISTOL,BRISTOL DENT SCH & HOSP,CTR STUDY ORAL DIS,DEPT ORAL MED,BRISTOL BS8 1TH,AVON,ENGLAND

来源：

ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTICS | 1991年 / 72卷 / 01期

关键词：

D O I：

10.1016/0030-4220(91)90188-I

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Antiviral drugs have proven effective in treatment of herpesvirus infections and in prevention of reactivation of latent virus. The prototype drug is acyclovir. Herpes simplex virus (HSV) is susceptible to acyclovir. There is increasing evidence in immunocompromised patients of acyclovir-resistant HSV causing clinical disease. Mechanisms of HSV resistance to acyclovir are known. These findings have implications for the future development and clinical use of antiviral drugs.

引用

页码：47 / 50

页数：4

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