MOLECULAR-CLONING AND CHARACTERIZATION OF A MOUSE-ALPHA-2C2 ADRENOCEPTOR SUBTYPE GENE

被引：10

作者：

CHEN, WM

CHANG, AC

SHIE, BJ

CHANG, YH

CHANG, NCA

机构：

[1] NATL YANG MING MED COLL,INST MICROBIOL & IMMUNOL,TAIPEI 11221,TAIWAN

[2] NATL YANG MING MED COLL,INST NEUROSCI,TAIPEI,TAIWAN

[3] NATL YANG MING MED COLL,INST CLIN MED,TAIPEI,TAIWAN

来源：

BIOCHIMICA ET BIOPHYSICA ACTA | 1992年 / 1171卷 / 02期

关键词：

ALPHA-2-ADRENOCEPTOR; MURINE GENOMIC CLONE;

D O I：

10.1016/0167-4781(92)90126-K

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A clone MA2C2 encoding the murine homologue of adrenoceptor alpha2C2 was isolated from a mouse genomic library using a subtype specific probe. The nucleotide and the deduced amino acid sequences derived from an ApaI fragment (2 kb) of the clone reveal a single open reading frame encoding a putative receptor protein of 455 amino acids. The 5' untranslated region (0.5 kb) sequenced is characterized by high GC content and CpG island count.

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页码：219 / 223

页数：5

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