WHOLE CELL CATALYZED KINETIC RESOLUTION OF 6-AZABICYCLO[3.2.0]HEPT-3-EN-7-ONE - SYNTHESIS OF (-)-CISPENTACIN (FR 109615)

被引：38

作者：

EVANS, C ^{[1
]}

MCCAGUE, R ^{[1
]}

ROBERTS, SM ^{[1
]}

SUTHERLAND, AG ^{[1
]}

WISDOM, R ^{[1
]}

机构：

[1] UNIV EXETER,DEPT CHEM,EXETER EX4 4RJ,DEVON,ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1991年 / 09期

关键词：

D O I：

10.1039/p19910002276

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Enantioselective hydrolysis of the beta-lactam (+/-)-2 using Rhodococcus equi provided (1R,5S)-6-azabicyclo[3.2.0]hept-3-en-7-one (+)-2, a precursor of the antifungal agent cispentacin.

引用

页码：2276 / 2277

页数：2

共 8 条

[1] BERGE JM, 1978, J CHEM RES-S, P255
[2] BERGE JM, 1978, J CHEM ES M, P3283
[3] THE TOTAL SYNTHESIS OF (+/-)-NAPHTHYRIDINOMYCIN .1. PREPARATION OF A KEY TRICYCLIC LACTAM INTERMEDIATE
EVANS, DA
BILLER, SA
[J]. TETRAHEDRON LETTERS, 1985, 26 (16) : 1907 - 1910
[4] IWAMOTO T, 1990, J ANTIBIOT, V43, P1
[5] SYNTHESIS AND STRUCTURE DETERMINATION OF FR109615, A NEW ANTIFUNGAL ANTIBIOTIC
KAWABATA, K
INAMOTO, Y
SAKANE, K
IWAMOTO, T
HASHIMOTO, S
[J]. JOURNAL OF ANTIBIOTICS, 1990, 43 (05) : 513 - 518
[6] CISPENTACIN, A NEW ANTIFUNGAL ANTIBIOTIC .1. PRODUCTION, ISOLATION, PHYSICOCHEMICAL PROPERTIES AND STRUCTURE
KONISHI, M
NISHIO, M
SAITOH, K
MIYAKI, T
OKI, T
KAWAGUCHI, H
[J]. JOURNAL OF ANTIBIOTICS, 1989, 42 (12) : 1749 - 1755
[7] CISPENTACIN, A NEW ANTIFUNGAL ANTIBIOTIC .2. INVITRO AND INVIVO ANTIFUNGAL ACTIVITIES
OKI, T
HIRANO, M
TOMATSU, K
NUMATA, KI
KAMEI, H
[J]. JOURNAL OF ANTIBIOTICS, 1989, 42 (12) : 1756 - 1762
[8] TAYLOR SJC, 1990, J CHEM SOC CHEM COMM, V6, P1120

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