DELTA FREQUENCY (1-4 HZ) OSCILLATIONS OF PERIGENICULATE THALAMIC NEURONS AND THEIR MODULATION BY LIGHT

被引:34
作者
AMZICA, F [1 ]
NUNEZ, A [1 ]
STERIADE, M [1 ]
机构
[1] UNIV LAVAL,FAC MED,NEUROPHYSIOL LAB,QUEBEC CITY G1K 7P4,QUEBEC,CANADA
关键词
D O I
10.1016/0306-4522(92)90315-S
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Neurons in the perigeniculate sector of the reticular thalamic nuclear complex were recorded extra- and intracellularly under deep urethane anesthesia. They were identified by burst responses to optic chiasm stimulation and depolarizing spindle oscillations in response to internal capsule stimulation. Perigeniculate neurons displayed oscillations within the frequency range of electroencephalogram delta waves (1-4 Hz). One-third of extracellularly recorded neurons discharged rhythmic (2.5-4 Hz), high-frequency (150-200 Hz) spike bursts. This was similar to an intrinsic oscillation that was recently observed in dorsal lateral geniculate cells studied in vitro and in vivo. Other oscillating neurons displayed trains of single spikes (20-50 Hz) crowning rhythmic (2.5-4 Hz) depolarizing envelopes that were best expressed at the "resting" membrane potential ( - 60 to - 65 mV). It is suggested that this oscillation reflects synaptic drives from dorsal lateral geniculate neurons. Changes in ambient room luminosity disrupted both types of delta rhythms. These data demonstrate for the first time that delta oscillations are present in the visual sector of the reticular thalamic nucleus. The results suggest that the two types of delta rhythmicity result from intrinsic and network properties of visual thalamic neurons and that perigeniculate cells may synchronize, through backward connections, the activity of dorsal lateral geniculate cells during deep stages of resting sleep.
引用
收藏
页码:285 / 294
页数:10
相关论文
共 31 条
  • [11] THE EFFECTS OF BRAIN-STEM PERIBRACHIAL STIMULATION ON PERIGENICULATE NEURONS - THE BLOCKAGE OF SPINDLE WAVES
    HU, B
    STERIADE, M
    DESCHENES, M
    [J]. NEUROSCIENCE, 1989, 31 (01) : 1 - 12
  • [12] LOW-FREQUENCY OSCILLATORY ACTIVITIES INTRINSIC TO RAT AND CAT THALAMOCORTICAL CELLS
    LERESCHE, N
    LIGHTOWLER, S
    SOLTESZ, I
    JASSIKGERSCHENFELD, D
    CRUNELLI, V
    [J]. JOURNAL OF PHYSIOLOGY-LONDON, 1991, 441 : 155 - 174
  • [13] Llinas R., 1988, CELLULAR THALAMIC ME, P23
  • [14] MCCORMICK DA, 1992, J NEUROSCI, V12, P278
  • [15] SEROTONIN AND NORADRENALINE EXCITE GABAERGIC NEURONS OF THE GUINEA-PIG AND CAT NUCLEUS RETICULARIS THALAMI
    MCCORMICK, DA
    WANG, Z
    [J]. JOURNAL OF PHYSIOLOGY-LONDON, 1991, 442 : 235 - 255
  • [16] NORADRENERGIC AND SEROTONERGIC MODULATION OF A HYPERPOLARIZATION-ACTIVATED CATION CURRENT IN THALAMIC RELAY NEURONS
    MCCORMICK, DA
    PAPE, HC
    [J]. JOURNAL OF PHYSIOLOGY-LONDON, 1990, 431 : 319 - 342
  • [17] PROPERTIES OF A HYPERPOLARIZATION-ACTIVATED CATION CURRENT AND ITS ROLE IN RHYTHMIC OSCILLATION IN THALAMIC RELAY NEURONS
    MCCORMICK, DA
    PAPE, HC
    [J]. JOURNAL OF PHYSIOLOGY-LONDON, 1990, 431 : 291 - 318
  • [18] MULLE C, 1986, J NEUROSCI, V6, P2143
  • [19] INTRACELLULAR EVIDENCE FOR INCOMPATIBILITY BETWEEN SPINDLE AND DELTA-OSCILLATIONS IN THALAMOCORTICAL NEURONS OF CAT
    NUNEZ, A
    DOSSI, RC
    CONTRERAS, D
    STERIADE, M
    [J]. NEUROSCIENCE, 1992, 48 (01) : 75 - 85
  • [20] INTRINSIC AND SYNAPTICALLY GENERATED DELTA (1-4HZ) RHYTHMS IN DORSAL LATERAL GENICULATE NEURONS AND THEIR MODULATION BY LIGHT-INDUCED FAST (30-70HZ) EVENTS
    NUNEZ, A
    AMZICA, F
    STERIADE, M
    [J]. NEUROSCIENCE, 1992, 51 (02) : 269 - 284