HIGHLY GENERAL-SYNTHESIS OF [E]- AND [Z]-3-ALKYLSUBSTITUTED ALLYLBORONATES VIA ONE-CARBON HOMOLOGATION OF STEREOSPECIFIC 1-ALKEN-1-YLBORONATES

被引：23

作者：

BROWN, HC

PHADKE, AS

BHAT, NG

机构：

[1] H. C. Brown and R. B. Wetherill Laboratories of Chemistry, Purdue University, West Lafayette

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 49期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1016/S0040-4039(00)61491-0

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Stereospecific 1-alken-1-ylboronates readily react with in situ generated chloromethyllithium, producing the corresponding allylboronate in good yields and in excellent stereochemical purities. These are very important synthetic intermediates and conversion of a representative derivative, [E]-2-(2-heptenyl)-1,3,2-dioxaborinane, 2 (R(1)=C4H9, R(2)=R(3)=H), into several compounds of synthetic interest is described.

引用

收藏

页码：7845 / 7848

页数：4

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