THE EFFECTS OF A RANGE OF ANTICANCER DRUGS IN THE WHITE-IVORY SOMATIC MUTATION TEST IN DROSOPHILA

被引：22

作者：

CLEMENTS, J

HOWE, D

LOWRY, A

PHILLIPS, M

机构：

[1] UNIV EXETER,WASHINGTON SINGER LABS,DEPT BIOL SCI,EXETER EX4 4QG,DEVON,ENGLAND

[2] TAUNTON & SOMERSET HOSP,MUSGROVE PK BRANCH,TAUNTON TA1 5DA,SOMERSET,ENGLAND

来源：

MUTATION RESEARCH | 1990年 / 228卷 / 02期

关键词：

D O I：

10.1016/0027-5107(90)90073-D

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The white-ivory test is based upon the reversion of the X-linked, recessive eye-colour mutation white-ivory to wild-type. Somatic reversion of white-ivory results in clones of red facets in the white-ivory eyes of eclosing adult files. 4 anti-cancer drugs, bleomycin, adriamycin, mitoxantrone and cyclophosphamide were found to significantly increase the white-ivory reversion frequency whereas cytosine arabinoside, methotrexate and vincristine did not give positive results. © 1990.

引用

页码：171 / 176

页数：6

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