CLINICAL AND LABORATORY OUTCOMES DURING THE TREATMENT OF RHEUMATOID-ARTHRITIS WITH METHOTREXATE

被引：10

作者：

CANNON, GW

READING, JC

WARD, JR

BLONQUIST, LJ

COLLETTE, LB

机构：

[1] VET ADM MED CTR,MED SERV,SALT LAKE CITY,UT 84148

[2] UNIV UTAH,SCH MED,DEPT FAMILY & COMMUNITY MED,SALT LAKE CITY,UT 84132

来源：

SCANDINAVIAN JOURNAL OF RHEUMATOLOGY | 1990年 / 19卷 / 04期

关键词：

C-reactive protein; Clinical outcomes measurements; Methotrexate; Rheumatoid arthritis; Rheumatoid factor; Westergren erythrocyte sedimentation rate;

D O I：

10.3109/03009749009102535

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Ten clinical and three laboratory outcomes were evaluated in 86 patients completing a double-blind placebo-controlled trial of methotrexate in rheumatoid arthritis. The improvement in all measured outcomes was statistically significantly better in patients receiving methotrexate than in patients receiving placebo. The correlations of the changes in outcome measures were calculated to determine if improvement in one parameter was associated with improvement in other clinical parameters. Associations between different clinical outcomes were often statistically significant. Associations between laboratory outcomes were also often statistically significant. However, the association between clinical outcomes and laboratory outcomes was generally poor. © 1990 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.

引用

页码：285 / 294

页数：10

共 26 条

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