INVITRO DIFFUSION IN POLYACRYLAMIDE EMBEDDED AGAROSE MICROBEADS

被引:6
作者
GIN, H [1 ]
DUPUY, B [1 ]
CAIX, J [1 ]
BAQUEY, C [1 ]
DUCASSOU, D [1 ]
机构
[1] UNIV BORDEAUX 2,INSERM,U 306,ZONE NORD,BAT 4,F-33076 BORDEAUX,FRANCE
关键词
D O I
10.3109/02652049009028420
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
125I Sodium iodide, 125I insulin, 125I albumin, and 111indium IGG were employed to investigate release from, and penetration of different sized molecules into agarose/polyacrylamide microcapsules. The microcapsules were formed by photopolymerization of an acrylamide solution round agarose beads. The indium-chelated antibody gave a particular low background count. The different release times were explained in terms of differences in diffusion coefficient. By retarding in vitro penetration of antibodies, these microcapsules could be of value for the encapsulation of living cells in bioartificial organs. © 1990 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted.
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收藏
页码:17 / 23
页数:7
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