ENTROPY IN BIOLOGICAL BINDING PROCESSES - ESTIMATION OF TRANSLATIONAL ENTROPY LOSS

被引：155

作者：

MURPHY, KP

XIE, D

THOMPSON, KS

AMZEL, LM

FREIRE, E

机构：

[1] JOHNS HOPKINS UNIV,SCH MED,DEPT BIOL,BALTIMORE,MD 21218

[2] JOHNS HOPKINS UNIV,CTR BIOCALORIMETRY,BALTIMORE,MD 21218

[3] JOHNS HOPKINS UNIV,SCH MED,DEPT BIOPHYS & BIOPHYS CHEM,BALTIMORE,MD 21205

来源：

PROTEINS-STRUCTURE FUNCTION AND GENETICS | 1994年 / 18卷 / 01期

关键词：

ENTROPY; THERMODYNAMICS; BINDING ENERGETICS; TRANSLATIONAL ENTROPY; MACROMOLECULAR INTERACTIONS;

D O I：

10.1002/prot.340180108

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The loss of translational degrees of freedom makes an important, unfavorable contribution to the free energy of binding. Examination of experimental values suggest that calculation of this entropy using the Sackur-Tetrode equation produces largely overestimated values. Better agreement is obtained using the cratic entropy. Theoretical considerations suggest that the volumes available for the movement of a ligand in solution and in a complex are rather similar, suggesting also that the cratic entropy provides the best estimate of the loss of translational entropy. (C) 1994 Wiley-Liss, Inc.

引用

页码：63 / 67

页数：5

共 21 条

[1] A MODEL FOR EVALUATION OF THERMODYNAMIC PROPERTIES FOR SOLID-SOLID AND MELTING TRANSITIONS OF MOLECULAR CRYSTALS
AMZEL, LM
BECKA, LN
[J]. JOURNAL OF PHYSICS AND CHEMISTRY OF SOLIDS, 1969, 30 (03) : 521 - &
[2] TEMPERATURE-DEPENDENCE OF THE HYDROPHOBIC INTERACTION IN PROTEIN FOLDING
BALDWIN, RL
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1986, 83 (21) : 8069 - 8072
[3] SIDE-CHAIN ENTROPY OPPOSES ALPHA-HELIX FORMATION BUT RATIONALIZES EXPERIMENTALLY DETERMINED HELIX-FORMING PROPENSITIES
CREAMER, TP
ROSE, GD
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1992, 89 (13) : 5937 - 5941
[4] THE PRICE OF LOST FREEDOM - ENTROPY OF BIMOLECULAR COMPLEX-FORMATION
FINKELSTEIN, AV
JANIN, J
[J]. PROTEIN ENGINEERING, 1989, 3 (01): : 1 - 3
[5] MOLECULAR-BASIS OF COOPERATIVITY IN PROTEIN-FOLDING .4. CORE - A GENERAL COOPERATIVE FOLDING MODEL
FREIRE, E
HAYNIE, DT
XIE, D
[J]. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 1993, 17 (02) : 111 - 123
[6] HORTON N, 1992, PROTEIN SCI, V1, P169
[7] SOME FACTORS IN THE INTERPRETATION OF PROTEIN DENATURATION
KAUZMANN, W
[J]. ADVANCES IN PROTEIN CHEMISTRY, 1959, 14 : 1 - 63
[8] PH-DEPENDENT PROCESSES IN PROTEINS
MATTHEW, JB
GURD, FRN
GARCIAMORENO, EB
FLANAGAN, MA
MARCH, KL
SHIRE, SJ
[J]. CRC CRITICAL REVIEWS IN BIOCHEMISTRY, 1985, 18 (02): : 91 - 197
[9] COMMON FEATURES OF PROTEIN UNFOLDING AND DISSOLUTION OF HYDROPHOBIC COMPOUNDS
MURPHY, KP
PRIVALOV, PL
GILL, SJ
[J]. SCIENCE, 1990, 247 (4942) : 559 - 561
[10] GROUP ADDITIVITY THERMODYNAMICS FOR DISSOLUTION OF SOLID CYCLIC DIPEPTIDES INTO WATER
MURPHY, KP
GILL, SJ
[J]. THERMOCHIMICA ACTA, 1990, 172 : 11 - 20

← 1 2 3 →