SEROLOGICAL STUDIES OF INFLUENZA-VIRUSES IN PIGS IN GREAT-BRITAIN 1991-2

被引：46

作者：

BROWN, IH

HARRIS, PA

ALEXANDER, DJ

机构：

[1] Virology Department, Central Veterinary Laboratory, Surrey KT15 3NB, New Haw, Addlestone

来源：

EPIDEMIOLOGY AND INFECTION | 1995年 / 114卷 / 03期

关键词：

D O I：

10.1017/S0950268800052225

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Samples from a sow serum bank representative of the pig population of Great Britain collected during 1991-2, were examined for antibodies to influenza A, B and C viruses, using viruses which had been isolated from a variety of hosts. For influenza-A viruses there was evidence of the continued circulation of classical swine' H1N1 virus (26 %) seroprevalence), and human H3N2 viruses (39 %) which are antigenically most closely-related to A/Port Chalmers/1/73 virus. In addition antibodies were detected to A/swine/England/201635/92 (8 %), a strain of H3N2 virus which appears to have arisen by antigenic drift from conventional H3N2 swine strains. Specific antibodies (2%) were detected to an H1N1. virus (A/swine/England/195852/99) related most closely to avian H1N1 strains. In tests with human H1N1 and H3N2 viruses, excluding isolates from pigs, the highest seroprevalence was detected to the prevailing strains from the human population. Serological tests with avian H4 and H10, human H2, equine 1 and 2 influenza A viruses were all negative. Seven pigs seropositive by haemagglutination-inhibition, virus neutralization and immunoblotting assays for antibody to influenza B virus, were randomly distributed geographically suggesting that influenza B viruses may be transmitted to pigs but fail to spread. The seroprevalence to influenza C viruses was 9.9 % indicating that these viruses are widespread in pigs. These results provide further evidence that the pig: can be infected by a number of influenza viruses, some of which may have significance in the epidemiology of human influenza.

引用

页码：511 / 520

页数：10

共 35 条

[21] Sugimura T., Yonemochi H., Ogawa T., Tanaka Y., Kumagai T., Isolation of a recombinant influenza virus (HswlN2) from swine in Japan, Arch Virol, 66, pp. 271-274, (1980)
[22] Castrucci M.R., Donatelli I., Sidoli L., Barigazzi G., Kawaoka Y., Webster R.G., Genetic reassortment between avian and human influenza A viruses in Italian pigs, Virology, 193, pp. 503-506, (1993)
[23] Gourreau J.M., Kaiser C., Valette M., Douglas A.R., Labie J., Armard M., Isolation of two H1N2 influenza viruses from swine in France, Arch Virol, 135, pp. 365-382, (1994)
[24] Goto H., Ogawa Y., Hirano T., Miwa Y., Piao F.Z., Takai M., Antibody responses of swine to type A influenza viruses during the past ten years in Japan, Epidemiol Infect, 100, pp. 523-526, (1988)
[25] Arikawa J., Yamane N., Odagiri T., Ishida N., Serological evidence of H1 influenza virus infection among Japanese hogs, Acta Virol, 23, pp. 508-511, (1979)
[26] Brown I.H., Chakraverty P., Harris P.A., Alexander D.J., Disease outbreaks in pigs in Great Britain due to an influenza A virus of H1N2 subtype, Vet Rec.
[27] Haesebrouck F., Biront B., Pensaert M.B., Leunen J., Epizootics of respiratory tract disease in swine in Belgium due to H3N2 influenza virus and experimental reproduction of disease, Am J Vet Res, 46, pp. 1926-1928, (1985)
[28] Brown I.H., Alexander D.J., Chakraverty P., Harris P.A., Manvell R.J., Isolation of an influenza A virus of unusual subtype (H1N7) from pigs in England, and the subsequent experimental transmission from pig to pig, Vet Micro, 39, pp. 125-134, (1994)
[29] Hinshaw V.S., Webster R.G., Easterday B.C., Bean W.J., Replication of avian influenza A viruses in mammals, Infect Immun, 81, pp. 354-361, (1981)
[30] Tumova B., Stumpa A., Madr V., Mensik J., Antibodies to new variants of subtype A (H3N2) influenza virus in pigs, Acta Virol, 29, pp. 150-153, (1985)

← 1 2 3 4 →