STEREOCHEMICAL STUDIES ON SOME VIC-BISPHOSPHONATES

被引：16

作者：

BLACKBURN, GM ^{[1
]}

FORSTER, AR ^{[1
]}

GUO, MJ ^{[1
]}

TAYLOR, GE ^{[1
]}

机构：

[1] AMERSHAM INT PLC,AMERSHAM HP7 9LL,BUCKS,ENGLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1991年 / 11期

关键词：

D O I：

10.1039/p19910002867

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The erythro- and racemic threo-forms of tetramethyl 1,2-dihydroxyethane-1,2-diylbisphosphonate have been identified and characterised by NMR analysis of their 2-ethoxy-1,3-dioxolane derivatives and by their independent conversion into tetramethyl cis- and trans-ethene-1,2-diylbisphosphonates respectively. Optimal conditions for the partial cis-reduction of tetraethyl ethyne-1,2-diylbisphosphonate have been identified. NMR data for the AA'XX' spectra of this range of two-carbon gem- and vicbisphosphonates are provided and discussed.

引用

页码：2867 / 2871

页数：5

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