THE DEVELOPMENT OF A MICROWAVE FLUID-BED PROCESSOR .1. CONSTRUCTION AND QUALIFICATION OF A PROTOTYPE LABORATORY UNIT

被引：10

作者：

DOELLING, MK ^{[1
]}

JONES, DM ^{[1
]}

SMITH, RA ^{[1
]}

NASH, RA ^{[1
]}

机构：

[1] ST JOHNS UNIV,COLL PHARM & ALLIED HLTH PROFESS,JAMAICA,NY 11439

来源：

PHARMACEUTICAL RESEARCH | 1992年 / 9卷 / 11期

关键词：

MICROWAVE DRYER; FLUID-BED DRYER; PROCESS EQUIPMENT VALIDATION;

D O I：

10.1023/A:1015875300053

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The static bed- and planetary-type microwave dryers currently available to process pharmaceutical materials are not designed to use hot-air fluidization for the purpose of maximizing microwave energy inputs and particle drying. To take advantage of the benefits offered by fluidization, a 1-kg Uni-Gatt laboratory fluid bed processor was modified to support microwave-assisted fluid bed drying of several representative pharmaceutical granulations. The construction, design features, and validation of this new microwave fluid bed processor are presented.

引用

页码：1487 / 1492

页数：6