MEDICAL PROGRESS - HEREDITARY GASTROINTESTINAL POLYPOSIS AND NONPOLYPOSIS SYNDROMES

被引：177

作者：

RUSTGI, AK ^{[1
]}

机构：

[1] HARVARD UNIV,SCH MED,BOSTON,MA

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 1994年 / 331卷 / 25期

关键词：

D O I：

10.1056/NEJM199412223312507

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Colon cancer is one of the most frequent cancers in men and women in the United States.1 There is a 6 percent lifetime risk of colon cancer in the general population.1 Approximately 160,000 new cases arise every year, and despite advances in detection and therapy, 60,000 people of colon cancer and its complications each year.2 Epidemiologic studies have implicated environmental factors in the pathogenesis of the disease. Support for these findings comes from the wide variations in the incidence of colon cancer among different populations.3 In Western societies, with diets high in fat and low in fiber, the rates. . . © 1994, Massachusetts Medical Society. All rights reserved.

引用

页码：1694 / 1702

页数：9

共 118 条

[11] 2-K
[12] BURT RW, 1984, GASTROENTEROLOGY, V86, P295
[13] BURT RW, 1988, GASTROENTEROL CLIN N, V17, P657
[14] BUSSEY HJR, 1978, GASTROENTEROLOGY, V74, P1325
[15] Bussey HJR, 1975, FAMILIAL POLYPOSIS C
[16] COMMON INHERITANCE OF SUSCEPTIBILITY TO COLONIC ADENOMATOUS POLYPS AND ASSOCIATED COLORECTAL CANCERS
CANNONALBRIGHT, LA
SKOLNICK, MH
BISHOP, T
LEE, RG
BURT, RW
[J]. NEW ENGLAND JOURNAL OF MEDICINE, 1988, 319 (09) : 533 - 537
[17] CARLSON HE, 1986, AM J HUM GENET, V38, P908
[18] COHEN PR, 1991, AM J MED, V90, P606
[19] GENERAL THEORY OF CARCINOGENESIS
COMINGS, DE
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1973, 70 (12) : 3324 - 3328
[20] A GENETIC MODEL FOR COLORECTAL TUMORIGENESIS
FEARON, ER
VOGELSTEIN, B
[J]. CELL, 1990, 61 (05) : 759 - 767

← 1 2 3 4 5 6 7 8 9 10 →