IS THE METABOLISM OF ALFENTANIL SUBJECT TO DEBRISOQUINE POLYMORPHISM - A STUDY USING HUMAN-LIVER MICROSOMES

被引：25

作者：

LAVRIJSEN, KLM

VANHOUDT, JMG

VANDYCK, DMJ

HENDRICKX, JJJM

WOESTENBORGHS, RJH

LAUWERS, W

MEULDERMANS, WEG

HEYKANTS, JJP

机构：

[1] JANSSEN RES FDN,DEPT DRUG METAB & PHARMACOKINET,TURNHOUTSEWEG 30,B-2340 BEERSE,BELGIUM

[2] JANSSEN RES FDN,DEPT ANALYT RES,B-2340 BEERSE,BELGIUM

来源：

ANESTHESIOLOGY | 1988年 / 69卷 / 04期

关键词：

D O I：

10.1097/00000542-198810000-00013

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

引用

页码：535 / 540

页数：6

共 29 条

[1] HUMAN CYTOCHROMES-P-450
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DAVIES, DS
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[2] BOOBIS AR, 1983, MOL PHARMACOL, V23, P474
[3] GENETIC-POLYMORPHISM IN DRUG OXIDATION - INVITRO STUDIES OF HUMAN DEBRISOQUINE 4-HYDROXYLASE AND BUFURALOL 1'-HYDROXYLASE ACTIVITIES
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[J]. BIOCHEMICAL PHARMACOLOGY, 1985, 34 (01) : 65 - 71
[4] BIPHASIC O-DEETHYLATION OF PHENACETIN AND 7-ETHOXYCOUMARIN BY HUMAN AND RAT-LIVER MICROSOMAL FRACTIONS
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DAVIES, DS
[J]. BIOCHEMICAL PHARMACOLOGY, 1981, 30 (17) : 2451 - 2456
[5] CHARACTERIZATION OF A HUMAN-LIVER CYTOCHROME-P-450 INVOLVED IN THE OXIDATION OF DEBRISOQUINE AND OTHER DRUGS BY USING ANTIBODIES RAISED TO THE ANALOGOUS RAT ENZYME
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[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1984, 81 (23): : 7348 - 7352
[6] A FAMILY AND POPULATION STUDY OF THE GENETIC-POLYMORPHISM OF DEBRISOQUINE OXIDATION IN A WHITE BRITISH-POPULATION
EVANS, DAP
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IDLE, JR
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[J]. JOURNAL OF MEDICAL GENETICS, 1980, 17 (02) : 102 - 105
[7] GREENLEE WF, 1978, J PHARMACOL EXP THER, V205, P596
[8] HUMAN-LIVER CYTOCHROMES-P-450 INVOLVED IN POLYMORPHISMS OF DRUG OXIDATION
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UMBENHAUER, DR
MARTIN, MV
[J]. XENOBIOTICA, 1986, 16 (05) : 367 - 378
[9] Henthorn T.K., 1985, ANESTHESIOLOGY, V63, pA305, DOI [10.1097/00000542-198509001-00305, DOI 10.1097/00000542-198509001-00305]
[10] HUGH CG, 1984, ALFENTANIL PHARM USE

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