CHARACTERIZATION OF A HUMAN-LIVER CYTOCHROME-P-450 INVOLVED IN THE OXIDATION OF DEBRISOQUINE AND OTHER DRUGS BY USING ANTIBODIES RAISED TO THE ANALOGOUS RAT ENZYME

被引：93

作者：

DISTLERATH, LM

GUENGERICH, FP

机构：

[1] VANDERBILT UNIV, MED CTR, SCH MED, DEPT BIOCHEM, NASHVILLE, TN 37232 USA

[2] VANDERBILT UNIV, MED CTR, SCH MED, CTR MOLEC TOXICOL, NASHVILLE, TN 37232 USA

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES | 1984年 / 81卷 / 23期

关键词：

D O I：

10.1073/pnas.81.23.7348

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：7348 / 7352

页数：5

共 24 条

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IDLE, JR
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[2] ISOLATION OF BIOLOGICALLY-ACTIVE RIBONUCLEIC-ACID FROM SOURCES ENRICHED IN RIBONUCLEASE
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[3] EVIDENCE FOR AN ENZYMATIC DEFECT IN THE 4-HYDROXYLATION OF DEBRISOQUINE BY HUMAN-LIVER
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[4] DEFECTIVE N-OXIDATION OF SPARTEINE IN MAN - NEW PHARMACOGENETIC DEFECT
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[5] EICHELBAUM M, 1982, CLIN PHARMACOKINET, V7, P1, DOI 10.2165/00003088-198207010-00001
[6] PURIFICATION AND CHARACTERIZATION OF LIVER MICROSOMAL CYTOCHROMES-P-450 - ELECTROPHORETIC, SPECTRAL, CATALYTIC, AND IMMUNOCHEMICAL PROPERTIES AND INDUCIBILITY OF 8 ISOZYMES ISOLATED FROM RATS TREATED WITH PHENOBARBITAL OR BETA-NAPHTHOFLAVONE
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WRIGHT, ST
MARTIN, MV
KAMINSKY, LS
[J]. BIOCHEMISTRY, 1982, 21 (23) : 6019 - 6030
[7] POLYMORPHISMS OF OXIDATION AT CARBON CENTERS OF DRUGS AND THEIR CLINICAL SIGNIFICANCE
IDLE, JR
SMITH, RL
[J]. DRUG METABOLISM REVIEWS, 1979, 9 (02) : 301 - 317
[8] HYPOTENSIVE RESPONSE TO DEBRISOQUINE AND HYDROXYLATION PHENOTYPE
IDLE, JR
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LANCASTER, R
SMITH, RL
[J]. LIFE SCIENCES, 1978, 22 (11) : 979 - 983
[9] ETHNIC-DIFFERENCES IN DRUG-METABOLISM
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[J]. CLINICAL PHARMACOKINETICS, 1982, 7 (05) : 373 - 400
[10] KUPFER A, 1983, SEMIN LIVER DIS, V3, P341, DOI 10.1055/s-2008-1040786

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