INDONESIAN MEDICINAL-PLANTS .4. ON THE CONSTITUENTS OF THE BARK OF FAGARA-RHETZA (RUTACEAE) .2. LIGNAN GLYCOSIDES AND 2 APIOGLUCOSIDES

被引：49

作者：

SHIBUYA, H ^{[1
]}

TAKEDA, Y ^{[1
]}

ZHANG, RS ^{[1
]}

TANITAME, A ^{[1
]}

TSAI, YL ^{[1
]}

KITAGAWA, I ^{[1
]}

机构：

[1] OSAKA UNIV, FAC PHARMACEUT SCI, 1-6 YAMADA-OKA, SUITA, OSAKA 565, JAPAN

来源：

CHEMICAL & PHARMACEUTICAL BULLETIN | 1992年 / 40卷 / 10期

关键词：

INDONESIAN MEDICINAL PLANT; FAGARA-RHETZA; RUTACEAE; LIGNAN GLYCOSIDE; HAZALEANIN; APIOGLUCOSIDE; LIGNAN CHIRAL SYNTHESIS;

D O I：

10.1248/cpb.40.2639

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Two new lignan glycosides, named hazaleanin A (1) and hazaleanin B (2), and two new apioglucosides, named isopropyl apioglucoside (3) and 4-hydroxyguaiacol apioglucoside (4), were isolated from the bark of Fagara rhetza (Rutaceae), an Indonesian medicinal plant from Flores Island, Indonesia. The chemical structures of 1, 2, 3, and 4 have been elucidated on the basis of chemical and physicochemical evidence, including a chiral synthesis of an aglycone derivative of 1.

引用

页码：2639 / 2646

页数：8

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