EMBRYONIC STEM-CELLS AND HOMOLOGOUS RECOMBINATION

被引:26
作者
FUNGLEUNG, WP
MAK, TW
机构
[1] RIV JOHNSON PHARMACEUT RES INST, TORONTO, ONTARIO, CANADA
[2] UNIV TORONTO, TORONTO M5S 1A1, ONTARIO, CANADA
关键词
D O I
10.1016/0952-7915(92)90012-4
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Mice with defined genetic defects can now be generated using gene targeting technology based on the successful generation of mouse embryonic stem cells with the potential for germ line transmission, and the development of methods for detection of homologous recombination.
引用
收藏
页码:189 / 194
页数:6
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