ANALYSIS OF LEUKOTRIENES, PROSTAGLANDINS, THROMBOXANE-B2 AND THEIR METABOLITES BY CAPILLARY ISOTACHOPHORESIS

被引：11

作者：

TSIKAS, D ^{[1
]}

FAULER, J ^{[1
]}

BRACHT, S ^{[1
]}

BRUNNER, G ^{[1
]}

FROLICH, JC ^{[1
]}

机构：

[1] HANNOVER MED SCH, DEPT GASTROENTEROL & HEPATOL, HANNOVER, GERMANY

来源：

ELECTROPHORESIS | 1993年 / 14卷 / 07期

关键词：

D O I：

10.1002/elps.11501401104

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

An analytical capillary isotachophoretic method for the analysis of the eicosanoids leukotriene E4, leukotriene B4, prostaglandins E1 and E2, 6-keto-prostaglandin F1alpha, thromboxane B2, and their metabolites of omega- and/or beta-oxidation is described. The method is based on anionic separation and detection by UV absorbance (254 nm) and conductivity and allows simultaneous analysis of the primary compounds and their corresponding major urinary metabolites. The method was applicable to the qualitative and quantitative analysis of prostaglandin E1 in a drug preparation.

引用

页码：664 / 666

页数：3

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