MICHAEL ADDITION OF POLY-L-LYSINE TO N-ACRYLOYLATED SIALOSIDES - SYNTHESES OF INFLUENZA-A VIRUS HEMAGGLUTININ INHIBITOR AND GROUP-B MENINGOCOCCAL POLYSACCHARIDE VACCINES

被引：25

作者：

ROY, R

PON, RA

TROPPER, FD

ANDERSSON, FO

机构：

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1993年 / 03期

关键词：

D O I：

10.1039/c39930000264

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

N-Acryloylated sialoside derivatives are directly conjugated to poly-L-lysine and protein carriers by the 1,4-conjugate additions of their N(epsilon)-lysine residues to provide new glycoconjugates with potential therapeutic utilities.

引用

页码：264 / 265

页数：2