A NEW INVITRO MODEL TO TEST THE EFFECTIVENESS OF TOPICAL ANTIMICROBIAL AGENTS - USE OF AN ARTIFICIAL ESCHAR

被引：10

作者：

HERRUZOCABRERA, R ^{[1
]}

VIZCAINOALCAIDE, MJ ^{[1
]}

MAYER, RF ^{[1
]}

REYCALERO, J ^{[1
]}

机构：

[1] AUTONOMOUS UNIV MADRID,DEPT PREVENT MED,MADRID,SPAIN

来源：

BURNS | 1992年 / 18卷 / 01期

关键词：

D O I：

10.1016/0305-4179(92)90117-D

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

An in vitro method using a burn eschar 'equivalent' is described to compare the efficacy of several antimicrobial creams. Fragments of lyophilized pigskin were used as 'germ carriers' and after 24 h of treatment the effectiveness of the antimicrobial creams was tested through the evaluation of bacterial recovery both from the surface and from within the 'germ carriers'. The results showed a striking full skin thickness effectiveness of 0.5 per cent chlorhexidine, 10 per cent povidone iodine and 2 per cent cerium nitrate in comparison with the weak activity demonstrated by 1 per cent silver sulphadiazine cream.

引用

页码：35 / 38

页数：4

共 15 条

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