UV MUTAGENESIS IN SALMONELLA-TYPHIMURIUM IS UMUDC DEPENDENT DESPITE THE PRESENCE OF SAMAB

被引：22

作者：

KOCH, WH

CEBULA, TA

FOSTER, PL

EISENSTADT, E

机构：

[1] OFF NAVAL RES,DIV BIOL SCI,800 N QUINCY ST,ARLINGTON,VA 22217

[2] US FDA,MOLEC BIOL BRANCH,WASHINGTON,DC 20204

[3] BOSTON UNIV,SCH PUBL HLTH,DIV ENVIRONM HLTH,BOSTON,MA 02118

来源：

JOURNAL OF BACTERIOLOGY | 1992年 / 174卷 / 09期

关键词：

D O I：

10.1128/JB.174.9.2809-2815.1992

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

We investigated the role of the umuDC and samAB operons in the UV mutability of Salmonella typhimurium. umuDC is located on the chromosome, whereas samAB resides on the virulence plasmid pSLT. Using allele replacement and plasmid curing techniques, we found that UV mutability was eliminated when any of three different umuDC alleles (umuD1, umuC1, or umuD1 umuC1) were on the chromosome even when samAB was present. We conclude that samAB normally does not complement umuDC function in S. typhimurium.

引用

页码：2809 / 2815

页数：7

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[11] FIDELITY MECHANISMS IN DNA-REPLICATION [J].