DIAGNOSIS OF TWIN ZYGOSITY BY HYPERVARIABLE RFLP MARKERS

被引：14

作者：

AKANE, A ^{[1
]}

MATSUBARA, K ^{[1
]}

SHIONO, H ^{[1
]}

YAMADA, M ^{[1
]}

NAKAGOME, Y ^{[1
]}

机构：

[1] NATL CHILDRENS MED RES CTR,DEPT CONGENITAL ABNORMALITIES RES,TOKYO,JAPAN

来源：

AMERICAN JOURNAL OF MEDICAL GENETICS | 1991年 / 41卷 / 01期

关键词：

DNA ANALYSIS; RESTRICTION FRAGMENT LENGTH POLYMORPHISM (RFLP); VARIABLE NUMBER OF TANDEM REPEAT (VNTR) MARKERS;

D O I：

10.1002/ajmg.1320410123

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The application of variable number of tandem repeat (VNTR) markers to the determination of twin zygosity was investigated. In the first case, which was performed with the use of six VNTR markers, the probability of monozygosity, calculated from Essen-Moller's formula II, was 0.99972. In the other three cases in which four VNTR markers were analyzed, the probabilities were 0.98251-0.99557. These results suggest that VNTR markers are useful for determination of twin zygosity.

引用

页码：96 / 98

页数：3

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