TESTING FOR HAPLOTYPE SHARING BY SIBLINGS WITH INCOMPLETE INFORMATION OF PARENTAL HAPLOTYPES

被引：9

作者：

GREEN, JR ^{[1
]}

GRENNAN, DM ^{[1
]}

机构：

[1] UNIV MANCHESTER,HOPE HOSP,CTR RHEUMAT DIS,MANCHESTER M13 9PL,LANCS,ENGLAND

来源：

ANNALS OF HUMAN GENETICS | 1991年 / 55卷

关键词：

D O I：

10.1111/j.1469-1809.1991.tb00419.x

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Testing for the inheritance of a disease susceptibility gene by analysis of haplotype sharing among affected siblings has been well established for the case where all four parental haplotypes have been ascertained. This paper presents a modification of a published method to cover the situation where there is incomplete information concerning parental haplotypes and this new test is applied in a worked example.

引用

页码：243 / 249

页数：7

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