NATURAL AND SYNTHETIC PEPTIDE POOLS - CHARACTERIZATION BY SEQUENCING AND ELECTROSPRAY MASS-SPECTROMETRY

被引：24

作者：

STEVANOVIC, S ^{[1
]}

WIESMULLER, KH ^{[1
]}

METZGER, J ^{[1
]}

BECKSICKINGER, AG ^{[1
]}

JUNG, G ^{[1
]}

机构：

[1] UNIV TUBINGEN,INST ORGAN CHEM,MORGENSTELLE 18,W-7400 TUBINGEN 1,GERMANY

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1993年 / 3卷 / 03期

关键词：

D O I：

10.1016/S0960-894X(01)80226-2

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Natural peptide pools consisting of octa- or nonapeptides and carrying defined anchor amino acids in at least two specific positions are bound to MHC-class I molecules. These isolated natural libraries and their synthetic analogues can be characterized by novel methods of multiple sequence analysis using automatic Edman degradation and electrospray mass spectrometry.

引用

页码：431 / 436

页数：6

共 9 条

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