RENAL-TRANSPLANT REJECTION - TRANSIENT IMMUNODOMINANCE OF HLA MISMATCHES

被引：29

作者：

GILKS, WR ^{[1
]}

GORE, SM ^{[1
]}

BRADLEY, BA ^{[1
]}

机构：

[1] UNITED KINGDOM TRANSPLANT SERV,BRISTOL BS10 SND,ENGLAND

来源：

TRANSPLANTATION | 1990年 / 50卷 / 01期

关键词：

D O I：

10.1097/00007890-199007000-00026

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Many studies have shown long-term benefits of HLA matching in kidney transplantation. By examining rates of graft loss within consecutive posttransplant intervals, using data from the UK Transplant Service, we show that the long-term benefits of HLA matching are due to reduction of the graft failure rate within five months of transplantation. After 5-months, HLA-A,B,DR matching appears to have little impact on graft loss. We suggest that graft losses after 5 months may be attributable to non-HLA targets. © 1990 by Williams & Wilkins.

引用

页码：141 / 146

页数：6