SIGNAL-TRANSDUCTION BY BETA-CATENIN

被引：355

作者：

GUMBINER, BM

机构：

[1] Cellular Biochemistry and Biophysics Program, Memorial Sloan-Kettering Cancer Center, New York, NY 10021

来源：

CURRENT OPINION IN CELL BIOLOGY | 1995年 / 7卷 / 05期

关键词：

D O I：

10.1016/0955-0674(95)80104-9

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

beta-catenin participates in signal transduction and developmental patterning in Xenopus and Drosophila embryos as a component of the Wnt signaling pathway. Its signaling activity is distinct from its role in cadherin-mediated cell adhesion, and it probably acts either in the cytosol or in the nucleus. The adenomatous polyposis coli tumor suppressor protein is also implicated in beta-catenin signaling.

引用

页码：634 / 640

页数：7